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Squaramide-Catalyzed Enantioselective Michael Addition of Diphenyl Phosphite to Nitroalkenes
Zhu, Ye; Malerich, Jeremiah P.; Rawal, Viresh H.

Michael's a square: An easily prepared squaramide catalyst that promotes the highly enantioselective Michael addition reaction of diphenyl phosphite to a range of nitroalkenes is described. This method leads to chiral β-nitro phosphonates, which are precursors to biologically active β-amino phosphonic acids.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION 49:1 (30 Nov. 2009): 153-56.
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